11 September 2006 The force on the surface of erythrocyte under laser irradiation
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Proceedings Volume 5967, 2004 Shanghai International Conference on Laser Medicine and Surgery; 59670J (2006) https://doi.org/10.1117/12.639188
Event: 2004 Shanghai international Conference on Laser Medicine and Surgery, 2004, Shanghai, China
Abstract
The intravenous low power laser irradiation has been applied clinically in china. However the mechanism is still not fully understood. In this work, the stretching force on the surface of erythrocyte under low power laser irradiation was explored. With the total internal reflection apparatus, the refractive indexes of hemoglobin cytoplasm in erythrocyte and the serum outside erythrocyte were determined as 1.380 and 1.351 respectively. Taking the sphere model for erythrocyte, the force on the surface of the erythrocyte due to the hitting of laser beam was calculated with the way of ray optics. It is found that the acting forces of laser on front and back surfaces are just in opposite direction, but with the similar magnitude of 10-2 PN. This couple forces act as the stretching forces to deform the erythrocyte, which may help erythrocytes to improve their deformability.
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J. T. Yu, J. T. Yu, J. Y. Chen, J. Y. Chen, J. Ma, J. Ma, D. X. Lee, D. X. Lee, L. Xu, L. Xu, P. N. Wang, P. N. Wang, } "The force on the surface of erythrocyte under laser irradiation", Proc. SPIE 5967, 2004 Shanghai International Conference on Laser Medicine and Surgery, 59670J (11 September 2006); doi: 10.1117/12.639188; https://doi.org/10.1117/12.639188
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