Prophylactic use of timolol maleate to prevent intraocular pressure elevation after Nd-YAG laser posterior capsulotomy

Jiping Cai; Ruili Wei; Xiaoye Ma; Huang Zhu; You Li; Jinwei Cheng; Feng Jiang

doi:10.1117/12.639340

11 September 2006 Prophylactic use of timolol maleate to prevent intraocular pressure elevation after Nd-YAG laser posterior capsulotomy

Jiping Cai, Ruili Wei, Xiaoye Ma, Huang Zhu, You Li, Jinwei Cheng, Feng Jiang

Author Affiliations +

Proceedings Volume 5967, 2004 Shanghai International Conference on Laser Medicine and Surgery; 59671L (2006) https://doi.org/10.1117/12.639340
Event: 2004 Shanghai international Conference on Laser Medicine and Surgery, 2004, Shanghai, China

Abstract

Objective: To evaluate the effective prophylaxis of topical 0.5% timolol maleate for the intraocular pressure rise following Nd-YAG laser posterior capsulotomy. Subjects and Methods: One hundred and ninety eyes of 184 patients undergoing Nd-YAG laser posterior capsulotomy were randomly assigned to pretreatment with either topical 0.5% timolol maleate (therapy group) or nothing (control group). Results: The mean IOP of the therapy group was 14.8±3.0 mmHg before capsulotomy and 15.7±3.4 mmHg after capsulotomy (P>0.05), whereas 15.1±3.3 mmHg and 17.2±4.3 mmHg (P<0.05) of the control group. There was no statistically significant difference between the two groups with regard to mean IOP before capsulotomy (P>0.05), but statistically significant difference between two groups after capsulotomy (P<0.05). Six of 91 eyes (6.6%, 2 aphakias included) of the therapy group had an IOP elevation greater than 6 mmHg compared with 14 of 99 eyes (14.1%, 8 aphakias included) of the control group (P<0.01). Conclusion: The pretreatment with topical 0.5% timolol maleate is effective in preventing IOP elevation after Nd-YAG laser posterior capsulotomy.

Citation Download Citation

Jiping Cai, Ruili Wei, Xiaoye Ma, Huang Zhu, You Li, Jinwei Cheng, and Feng Jiang "Prophylactic use of timolol maleate to prevent intraocular pressure elevation after Nd-YAG laser posterior capsulotomy", Proc. SPIE 5967, 2004 Shanghai International Conference on Laser Medicine and Surgery, 59671L (11 September 2006); https://doi.org/10.1117/12.639340

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KEYWORDS

Nd:YAG lasers

Laser therapeutics

Visualization

Surgery

Eye

Statistical analysis

Laser safety

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