25 October 2005 A selective laser irradiation technique using a spatial light modulator
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Technological advances in medicine are often directed towards the development of minimally invasive treatment modalities. The spatial selectivity of irradiation and the dose control are essential criteria's that influence the effectiveness of a laser treatment. We propose a new irradiation technique to improve the laser irradiation selectivity and dose control. The technique is based on the use of a spatial light modulator to project a'rectangular laser image of 8×5mm in our prototype. The spatial distribution of the irradiation is controlled in real time by image analysis to discriminate between the target area to be irradiated and the surrounding parts to be preserved. This technique is able to achieve a multi targets irradiation simultaneously. The resolution is about 12μm and is only limited by the camera resolution. Thanks to a collinear optical scheme, the calibration of the system is simple and robust. The duration of the control loop between image acquisition and laser treatment can be less than 200ms for the entire image (depending on the image analysis complexity).
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Faouzi Gassem, Faouzi Gassem, René Farcy, René Farcy, "A selective laser irradiation technique using a spatial light modulator", Proc. SPIE 5968, Laser Florence 2004: A Window on the Laser Medicine World, 59680E (25 October 2005); doi: 10.1117/12.660054; https://doi.org/10.1117/12.660054

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