Preliminary results: exploring the interactions of quantum dots with whole blood components

Hans C. Fischer; Eliseo Papa; Lichuan Liu; K. Sandy Pang; Warren C. W. Chan

doi:10.1117/12.629344

12 October 2005 Preliminary results: exploring the interactions of quantum dots with whole blood components

Hans C. Fischer, Eliseo Papa, Lichuan Liu, K. Sandy Pang, Warren C. W. Chan

Author Affiliations +

Proceedings Volume 5969, Photonic Applications in Biosensing and Imaging; 59690E (2005) https://doi.org/10.1117/12.629344
Event: Photonics North, 2005, Toronto, Canada

Abstract

Biocompatible ZnS capped CdSe fluorescent semiconductor nanocrystals (quantum dots, QDs) exhibit great potential as imaging agents with biomedical and clinical relevance. However, little is known about the fate of the quantum dots in vivo, and the importance of chemical and physical composition that may influence their behavior in vivo. When the QDs are introduced in vivo, the first interactions with blood components will dictate their kinetic behavior in vivo. We present some preliminary results that demonstrate the interactions of the quantum dots with plasma proteins and that quantum dots can be trapped in fibrous networks.

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Hans C. Fischer, Eliseo Papa, Lichuan Liu, K. Sandy Pang, and Warren C. W. Chan "Preliminary results: exploring the interactions of quantum dots with whole blood components", Proc. SPIE 5969, Photonic Applications in Biosensing and Imaging, 59690E (12 October 2005); https://doi.org/10.1117/12.629344

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