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12 October 2005 Biomolecule-less sensors for biomolecules based on templated xerogel platforms
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Abstract
We report on a new strategy for producing self-contained sensor elements for protein detection. The method exploits molecular imprinting, sol-gel-derived xerogels, and selective installation of the fluorescent reporter molecule within the template site. There are no biological reagents used. We term these new xerogel-based sensor elements as Protein Imprinted Xerogels with Integrated Emission Sites (PIXIES). The analytical figures of merit are described.
© (2005) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Zunyu Tao, Elizabeth C. Tehan, Rachel M. Bukowski, Ying Tang, Ellen L. Shughart, William G. Holthoff, Alexander N. Cartwright, Albert H. Titus, and Frank V. Bright "Biomolecule-less sensors for biomolecules based on templated xerogel platforms", Proc. SPIE 5969, Photonic Applications in Biosensing and Imaging, 59690F (12 October 2005); https://doi.org/10.1117/12.629169
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