13 October 2005 UV radiation, vitamin D, and cancer: how to measure the vitamin D synthetic capacity of UV sources?
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Abstract
UV irradiation is widely used in phototherapy. Regardless of the fact that UV overexposure is liable to cause adverse health effect, in appropriate doses UV radiation initiates synthesis of vitamin D in skin that is absolutely essential for human health. As it proved, most people in northern industrial countries have a level of vitamin D in their bodies that is insufficient for optimum health, especially in winter. These low levels of vitamin D are now known to be associated with a wide spectrum of serious disease much of which leads on to premature death. The diseases associated with D deficiency involve more than a dozen types of cancer including colon, breast and prostate, as well as the classic bone diseases: rickets, osteoporosis and osteomalacia. Irradiation with artificial UV sources can prevent the vitamin D deficiency. However, in view of different irradiation spectra of UV lamps, their ability to initiate vitamin D synthesis is different. The reliable method based on an in vitro model of vitamin D synthesis has been developed for direct measurement in situ of the vitamin D synthetic capacity of artificial UV sources during a phototherapeutic procedure
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Irina Terenetskaya, Tatiana Orlova, "UV radiation, vitamin D, and cancer: how to measure the vitamin D synthetic capacity of UV sources?", Proc. SPIE 5969, Photonic Applications in Biosensing and Imaging, 596920 (13 October 2005); doi: 10.1117/12.628286; https://doi.org/10.1117/12.628286
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