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13 October 2005 UV radiation, vitamin D, and cancer: how to measure the vitamin D synthetic capacity of UV sources?
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UV irradiation is widely used in phototherapy. Regardless of the fact that UV overexposure is liable to cause adverse health effect, in appropriate doses UV radiation initiates synthesis of vitamin D in skin that is absolutely essential for human health. As it proved, most people in northern industrial countries have a level of vitamin D in their bodies that is insufficient for optimum health, especially in winter. These low levels of vitamin D are now known to be associated with a wide spectrum of serious disease much of which leads on to premature death. The diseases associated with D deficiency involve more than a dozen types of cancer including colon, breast and prostate, as well as the classic bone diseases: rickets, osteoporosis and osteomalacia. Irradiation with artificial UV sources can prevent the vitamin D deficiency. However, in view of different irradiation spectra of UV lamps, their ability to initiate vitamin D synthesis is different. The reliable method based on an in vitro model of vitamin D synthesis has been developed for direct measurement in situ of the vitamin D synthetic capacity of artificial UV sources during a phototherapeutic procedure
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Irina Terenetskaya and Tatiana Orlova "UV radiation, vitamin D, and cancer: how to measure the vitamin D synthetic capacity of UV sources?", Proc. SPIE 5969, Photonic Applications in Biosensing and Imaging, 596920 (13 October 2005);

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