A transducer-independent optical sensor system for the detection of biochemical binding reactions

Rüdiger Frank; Bernd Möhrle; Dieter Fröhlich; Günter Gauglitz

doi:10.1117/12.633881

8 November 2005 A transducer-independent optical sensor system for the detection of biochemical binding reactions

Rüdiger Frank, Bernd Möhrle, Dieter Fröhlich, Günter Gauglitz

Proceedings Volume 5993, Advanced Environmental, Chemical, and Biological Sensing Technologies III; 59930A (2005) https://doi.org/10.1117/12.633881
Event: Optics East 2005, 2005, Boston, MA, United States

Abstract

In this article we present a very simple, transducer-independent label-free optical detection method based on reflectometry for bioanalytical applications. A laboratory setup of this 1λ-reflectometry delivers results that are comparable with established detection principles like Surface Plasmon Resonance or Reflectometric Interference Spectroscopy. Additionally we present a first version of a miniaturized setup of this method to show its potential due to its simplicity.

Citation Download Citation

Rüdiger Frank, Bernd Möhrle, Dieter Fröhlich, and Günter Gauglitz "A transducer-independent optical sensor system for the detection of biochemical binding reactions", Proc. SPIE 5993, Advanced Environmental, Chemical, and Biological Sensing Technologies III, 59930A (8 November 2005); https://doi.org/10.1117/12.633881

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