Photoacoustic imaging with focused ultrasonic probe beam

Liangzhong Xiang; Huaimin Gu

doi:10.1117/12.709928

27 October 2006 Photoacoustic imaging with focused ultrasonic probe beam

Liangzhong Xiang, Huaimin Gu

Proceedings Volume 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine; 60470H (2006) https://doi.org/10.1117/12.709928
Event: Fourth International Conference on Photonics and Imaging in Biology and Medicine, 2005, Tianjin, China

Abstract

This paper presents a novel model of photoacoustic tomography with an ultrasonic probe beam. A strict theory describes the nonlinear interaction between photoacoustic wave and ultrasonic probe beam. When a pulse laser irradiates on biological tissues, the laser energy will be absorbed by the identity molecule of the tissues, and be converted into heat. Subsequently, the thermal expansion of the instantaneously heated tissues induces photoacoustic waves. So the density, temperature and compressibility of the absorption area will be changed. A focus ultrasonic probe beam with a single frequency passes through the irradiated area, the changes of the properties of the irradiated medium will be coupled with the ultrasonic probe beam, which will propagate through the medium with minimal distortion and can be detected at the surface of the medium. The PA signal in situ can be obtained by demodulating the detected ultrasonic beam. It will take out much more information from the interaction area, which can reflect not only the intrinsic optical properties but also the mechanical and acoustical properties of the tissue. In our experimentation, a Q-switched Nd: YAG pulse laser operated at 1064nm was employed to generate photoacoustic signal, the frequency of ultrasonic probe beam is l0M. By demodulating the detected ultrasonic beam, we obtained very high quality tomography images. So it will provide a new promising method for tumour detection and noninvasion function imaging.

Citation Download Citation

Liangzhong Xiang and Huaimin Gu "Photoacoustic imaging with focused ultrasonic probe beam", Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 60470H (27 October 2006); https://doi.org/10.1117/12.709928

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KEYWORDS

Tissues

Laser beam diagnostics

Ultrasonics

Photoacoustic spectroscopy

Absorption

Pulsed laser operation

Photoacoustic tomography

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