27 October 2006 An event-related analysis of P300 by simultaneous EEG/fMRI
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Proceedings Volume 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine; 60472S (2006) https://doi.org/10.1117/12.710992
Event: Fourth International Conference on Photonics and Imaging in Biology and Medicine, 2005, Tianjin, China
Abstract
In this study, P300 that induced by visual stimuli was examined with simultaneous EEG/fMRI. For the purpose of combine the best temporary resolution with the best special resolution together to estimate the brain function, event-related analysis contributed to this methodological trial. A 64 channel MRT-compatible MR EEG amplifier (BrainAmp: made of Brain Production GmbH, Gennany) was used in the measurement simultaneously with fMRI scanning. The reference channel is between Fz, Cz and Pz. Sampling rate of raw EEG was 5 kHz, and the MRT noise reduction was performed. EEG recording synchronized with MRI scan by our original stimulus system, and an oddball paradigm (four-oriented Landolt Ring presentation) was performed in the official manner. After P300 segmentation, the timing of P300 was exported to event-related analysis of fMRI data with SPM99 software. In single subject study, the significant activations appear in the left superior frontal, Broca's area and on both sides of the parietal lobule when P300 occurred. It is suggest that P300 may be an integration carried out by top-down signal from frontal to the parietal lobule, which regulates an Attention-Logical Judgment process. Compared with other current methods, the event related analysis by simultaneous EEG/IMRI is excellent in the point that can describe the cognitive process with reality unifying further temporary and spatial information. It is expected that examination and demonstration of the obtained result will supply with the promotion of this powerful methods.
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Li-qun Wang, Li-qun Wang, Mingshi Wang, Mingshi Wang, Hiroaki Mizuhara, Hiroaki Mizuhara, } "An event-related analysis of P300 by simultaneous EEG/fMRI", Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 60472S (27 October 2006); doi: 10.1117/12.710992; https://doi.org/10.1117/12.710992
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