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20 February 2006 Three-dimensional time and Fourier domain endoscopic OCT using 2-axis scanning MEMS mirror
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We present a three-dimensional (3-D) endoscopic optical coherence tomography (OCT) system based on a dual axis microelectromechanical system (MEMS) mirror. The diameter of MEMS mirror was 1.2 mm and both axes were capable of scanning up to 20° (optical) at greater than 1 kHz with excellent linearity. The MEMS mirror was packaged in a machined acrylic endoscopic housing which provided mechanical protection and electrical interconnects as well as optical alignment of the MEMS device to a focusing GRIN lens. The endoscopic MEMS probe was integrated and tested with both a fiber-based time domain (TD) OCT system and Fourier domain (FD) OCT system. Combining the 2-axis lateral scanning of the MEMS device with an axial scan allowed 3-D volume images to be obtained at a rate of 3 frames/s for the TD system and 7 frames/s for the FD system. In the initial investigations, in vivo 3-D OCT images of a human finger as well as images of animal tissue such as healthy rabbit trachea, normal and cancerous regions of hamster cheek pouch tissue were obtained. These images allowed real-time diagnosis of diseased tissue and also clearly delineated important features and tissue structures.
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Woonggyu Jung, Daniel T. McCormick, Yeh-Chan Ahn, Jun Zhang, Norman C. Tien, and Zhongping Chen "Three-dimensional time and Fourier domain endoscopic OCT using 2-axis scanning MEMS mirror", Proc. SPIE 6079, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X, 60791I (20 February 2006);

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