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20 February 2006 In vivo blood flow imaging by swept-source-based Fourier domain optical Doppler tomography
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Abstract
A swept source based Fourier domain optical Doppler tomography (FDODT) system was developed. The technique is based on a phase resolved method where phase information was retrieved from the reconstructed complex fringe signals. The aliasing effects and artifacts caused by lateral scanning and sample movement were removed with a signal processing technique. The standard deviation of the phase shift of the system was reduced from 49 to 1.8 degree with the signal processing method employed. Structural and Doppler images of fluid flow through glass channels were quantified and blood flow through vessels of chick chorioallantoic membrane (CAM) were demonstrated in vivo.
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Jun Zhang and Zhongping Chen "In vivo blood flow imaging by swept-source-based Fourier domain optical Doppler tomography", Proc. SPIE 6079, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X, 607920 (20 February 2006); https://doi.org/10.1117/12.649096
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