20 February 2006 Noise model for polarization-sensitive optical coherence tomography
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Characterizing and quantifying noise sources in birefringence imaging with polarization-sensitive optical coherence tomography (PS-OCT) is necessary for the development of efficient noise reduction techniques for real-time clinical PS-OCT imaging. We propose three noise regimes based on the strength of specimen backscattering and dominated by different noise sources. We introduce a model that predicts noise effects in two regimes. The model includes source/detector intensity noise, and couples speckle effects with the longitudinal delays due to instrument and specimen birefringence to create realistic noise on simulated orthogonal interference fringe amplitudes and on their relative phases. Experimental examples of the three regimes are presented and in two of them, qualitative agreement between the model and experimental data is demonstrated.
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Paul A. Williams, Paul A. Williams, Nate J. Kemp, Nate J. Kemp, David Ives, David Ives, Jesung Park, Jesung Park, Jordan C. Dwelle, Jordan C. Dwelle, H. Grady Rylander III, H. Grady Rylander III, Thomas E. Milner, Thomas E. Milner, } "Noise model for polarization-sensitive optical coherence tomography", Proc. SPIE 6079, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine X, 607929 (20 February 2006); doi: 10.1117/12.649094; https://doi.org/10.1117/12.649094

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