Multi-modality molecular imaging:  pre-clinical laboratory configuration

Yanjun Wu; Jeremy W. Wellen; Susanta K. Sarkar

doi:10.1117/12.660244

13 February 2006 Multi-modality molecular imaging: pre-clinical laboratory configuration

Yanjun Wu, Jeremy W. Wellen, Susanta K. Sarkar

Proceedings Volume 6081, Multimodal Biomedical Imaging; 60810H (2006) https://doi.org/10.1117/12.660244
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

In recent years, the prevalence of in vivo molecular imaging applications has rapidly increased. Here we report on the construction of a multi-modality imaging facility in a pharmaceutical setting that is expected to further advance existing capabilities for in vivo imaging of drug distribution and the interaction with their target. The imaging instrumentation in our facility includes a microPET scanner, a four wavelength time-domain optical imaging scanner, a 9.4T/30cm MRI scanner and a SPECT/X-ray CT scanner. An electronics shop and a computer room dedicated to image analysis are additional features of the facility. The layout of the facility was designed with a central animal preparation room surrounded by separate laboratory rooms for each of the major imaging modalities to accommodate the work-flow of simultaneous in vivo imaging experiments. This report will focus on the design of and anticipated applications for our microPET and optical imaging laboratory spaces. Additionally, we will discuss efforts to maximize the daily throughput of animal scans through development of efficient experimental work-flows and the use of multiple animals in a single scanning session.

Citation Download Citation

Yanjun Wu, Jeremy W. Wellen, and Susanta K. Sarkar "Multi-modality molecular imaging: pre-clinical laboratory configuration", Proc. SPIE 6081, Multimodal Biomedical Imaging, 60810H (13 February 2006); https://doi.org/10.1117/12.660244

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