Nonlinear image reconstruction algorithm for diffuse optical tomography using iterative block solver and automatic mesh generation from tomosynthesis images

Qianqian Fang; David Boas; Greg Boverman; Quan Zhang; Tina Kauffman

doi:10.1117/12.662689

13 February 2006 Nonlinear image reconstruction algorithm for diffuse optical tomography using iterative block solver and automatic mesh generation from tomosynthesis images

Qianqian Fang, David Boas, Greg Boverman, Quan Zhang, Tina Kauffman

Author Affiliations +

Proceedings Volume 6081, Multimodal Biomedical Imaging; 60810O (2006) https://doi.org/10.1117/12.662689
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

In this paper, we report a nonlinear 3D image reconstruction algorithm featuring 3D finite element forward modeling with an iterative multi-right-hand-side solver and an automatic mesh generation technique for efficient geometry modeling. The forward mesh was generated based on 3D tomosynthesis images acquired simultaneously with optical measurements. An efficient iterative solver based on a QMR algorithm with the capacity of solving multi-RHS was used to enhance the computational efficiency. The mesh generation algorithm was developed based on a moving mesh process and is able to generate high-quality mesh with low computational complexity. In addition, an approximated adjoint method was used to form the Jacobian matrix for the inverse problem. The performance was satisfactory in numerical simulations. For a typical reconstruction, the run-time was under 5 minutes on a Pentium-based PC. It is worth mentioning that the mesh generation module not only works for binary 2D or 3D image stacks, but also for any other binary description of the object, which makes it generalizable to many other potential applications.

Citation Download Citation

Qianqian Fang, David Boas, Greg Boverman, Quan Zhang, and Tina Kauffman "Nonlinear image reconstruction algorithm for diffuse optical tomography using iterative block solver and automatic mesh generation from tomosynthesis images", Proc. SPIE 6081, Multimodal Biomedical Imaging, 60810O (13 February 2006); https://doi.org/10.1117/12.662689

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