128-channel laser optoacoustic imaging system (LOIS-128) for breast cancer diagnostics

Sergey A. Ermilov; Andre Conjusteau; Ketan Mehta; Ron Lacewell; P. Mark Henrichs; Alexander A. Oraevsky

doi:10.1117/12.658158

6 March 2006 128-channel laser optoacoustic imaging system (LOIS-128) for breast cancer diagnostics

Sergey A. Ermilov, Andre Conjusteau, Ketan Mehta, Ron Lacewell, P. Mark Henrichs, Alexander A. Oraevsky

Proceedings Volume 6086, Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; 608609 (2006) https://doi.org/10.1117/12.658158
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

We have designed, fabricated and tested a new 128-channel laser optoacoustic imaging system (LOIS-128) for cancer diagnostics consisting of an acoustic probe with 128 PVDF transducers, a digital signal processor with 128 independent channels, and software for reconstruction of optoacoustic images. The system was capable of continuous planar imaging (at rates up to 1 Hz) of small (less than 1 cm) tumors at depths over 6 cm. The directivity of the optoacoustic transducers used in LOIS-128 assured that signal detection at all angles within a narrow imaging slice was at least 40% of the maximal signal. The signal detection was better than 70% of the maximum for about 75% of the image in the image slice and close to zero for signals coming from out of the image slice. LOIS-128 could image high-aspect-ratio objects with about 0.5 mm resolution. Finally, with the designed image reconstruction algorithm we were able to estimate absorption coefficients for test objects with accuracy of at least 5%.

Citation Download Citation

Sergey A. Ermilov, Andre Conjusteau, Ketan Mehta, Ron Lacewell, P. Mark Henrichs, and Alexander A. Oraevsky "128-channel laser optoacoustic imaging system (LOIS-128) for breast cancer diagnostics", Proc. SPIE 6086, Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 608609 (6 March 2006); https://doi.org/10.1117/12.658158

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