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6 March 2006 128-channel laser optoacoustic imaging system (LOIS-128) for breast cancer diagnostics
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Abstract
We have designed, fabricated and tested a new 128-channel laser optoacoustic imaging system (LOIS-128) for cancer diagnostics consisting of an acoustic probe with 128 PVDF transducers, a digital signal processor with 128 independent channels, and software for reconstruction of optoacoustic images. The system was capable of continuous planar imaging (at rates up to 1 Hz) of small (less than 1 cm) tumors at depths over 6 cm. The directivity of the optoacoustic transducers used in LOIS-128 assured that signal detection at all angles within a narrow imaging slice was at least 40% of the maximal signal. The signal detection was better than 70% of the maximum for about 75% of the image in the image slice and close to zero for signals coming from out of the image slice. LOIS-128 could image high-aspect-ratio objects with about 0.5 mm resolution. Finally, with the designed image reconstruction algorithm we were able to estimate absorption coefficients for test objects with accuracy of at least 5%.
© (2006) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Sergey A. Ermilov, Andre Conjusteau, Ketan Mehta, Ron Lacewell, P. Mark Henrichs, and Alexander A. Oraevsky "128-channel laser optoacoustic imaging system (LOIS-128) for breast cancer diagnostics", Proc. SPIE 6086, Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 608609 (6 March 2006); https://doi.org/10.1117/12.658158
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