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6 March 2006 Optical and mechanical properties in photorefractive crystal based ultrasound-modulated optical tomography
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Abstract
Ultrasound-modulated optical tomography (UOT) is a new technique that combines laser light and ultrasound to provide images with good optical contrast and good ultrasound resolution in soft biological tissue. We improve the method proposed by Murray et al to obtain UOT images in thick biological tissues with the use of photorefractive crystal based interferometers. It is found that a long ultrasound burst (on the order of a millisecond) can improve the signal-to-noise ratio dramatically. Also with a long ultrasound burst, the response of the acoustic radiation force impulses can be clearly observed in the UOT signal, which will help to acquire images that record both the optical and mechanical properties of biological soft tissues.
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Huiliang Zhang, Xiao Xu, De-Kui Qing, Philip Hemmer, and Lihong V. Wang "Optical and mechanical properties in photorefractive crystal based ultrasound-modulated optical tomography", Proc. SPIE 6086, Photons Plus Ultrasound: Imaging and Sensing 2006: The Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics, 608616 (6 March 2006); https://doi.org/10.1117/12.646155
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