Multiphoton nanosurgery in cells and tissues

Iris Riemann; Frank Stracke; Daniel Sauer; Sven Martin; Karsten König

doi:10.1117/12.646096

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23 February 2006 Multiphoton nanosurgery in cells and tissues

Iris Riemann, Frank Stracke, Daniel Sauer, Sven Martin, Karsten König

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Proceedings Volume 6089, Multiphoton Microscopy in the Biomedical Sciences VI; 608918 (2006) https://doi.org/10.1117/12.646096
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

Near infrared (NIR) femtosecond laser microscopes enable the user to perform highly precise nanosurgery. Tissue components, cells and single organelles of cells inside tumor-sphaeroids and tissues can be precisely manipulated and optically knocked out without collateral damage. In addition, the monitoring effects of nanosurgery in situ using two photon excitation of auto fluorescence of endogenous fluorophores can be performed quite easily with a sub-cellular resolution. This method may become a useful instrument for nano manipulation and nano-surgery in several fields of life sciences.

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Iris Riemann, Frank Stracke, Daniel Sauer, Sven Martin, and Karsten König "Multiphoton nanosurgery in cells and tissues", Proc. SPIE 6089, Multiphoton Microscopy in the Biomedical Sciences VI, 608918 (23 February 2006); https://doi.org/10.1117/12.646096

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