Fluorescence-based microendoscopes for breast cancer ductoscopy

Iosif Zeylikovich; Guichen C. Tang; A. Katz; Yury Budansky; R. R. Alfano

doi:10.1117/12.646203

22 February 2006 Fluorescence-based microendoscopes for breast cancer ductoscopy

Iosif Zeylikovich, Guichen C. Tang, A. Katz, Yury Budansky, R. R. Alfano

Proceedings Volume 6091, Optical Biopsy VI; 609102 (2006) https://doi.org/10.1117/12.646203
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

Recently microendoscopes are being developed as a tool to detection cancer or pre-cancerous lesions in the milk ducts of the human breast. The microendoscope can be inserted into the duct through the nipple. Integration of fluorescence spectroscopy into microendoscopy can provide an improved platform for real-time cancer detection followed by immediate intervention. Typically, the optical fibers employed by existing microendoscope systems transmit in the 450 to 900 nm range. A prototype system combining fluorescence spectroscopy with visible imaging by microendoscopy is described and preliminary measurements on ex vivo human breast tissues are presented. Image resolution and distortion are discussed.

Citation Download Citation

Iosif Zeylikovich, Guichen C. Tang, A. Katz, Yury Budansky, and R. R. Alfano "Fluorescence-based microendoscopes for breast cancer ductoscopy", Proc. SPIE 6091, Optical Biopsy VI, 609102 (22 February 2006); https://doi.org/10.1117/12.646203

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available