27 February 2006 Advances in the development of a novel method to be used in proteomics using gold nanobeads
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Abstract
The study of DNA-protein interactions is gaining increased attention due to their importance in cellular processes. Only a well-functioning interaction guaranties that such a process can take place without errors. So far, only a small percentage of these interactions have been unraveled, partially due to their complexity but also due to the fact that there are only a few techniques that permit the study of these interactions. In this report we describe the development of a research tool based on tethered bead motion and Resonance Light Scattering (RLS) from gold beads. This method permits the study of DNA-protein interactions and the screening of proteins binding to a specific DNA sequence.
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Heidelinde R. C. Dietrich, Heidelinde R. C. Dietrich, Ian T. Young, Ian T. Young, Yuval Garini, Yuval Garini, } "Advances in the development of a novel method to be used in proteomics using gold nanobeads", Proc. SPIE 6092, Ultrasensitive and Single-Molecule Detection Technologies, 60920C (27 February 2006); doi: 10.1117/12.645908; https://doi.org/10.1117/12.645908
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