Blood compatibility of artificial blood vessels probed by infrared spectroscopic imaging

Gerald Steiner; Manfred Maitz; Sibel Tunc; Reiner Salzer

doi:10.1117/12.644997

10 February 2006 Blood compatibility of artificial blood vessels probed by infrared spectroscopic imaging

Gerald Steiner, Manfred Maitz, Sibel Tunc, Reiner Salzer

Proceedings Volume 6093, Biomedical Vibrational Spectroscopy III: Advances in Research and Industry; 609302 (2006) https://doi.org/10.1117/12.644997
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

The determination of protein structure and function plays an important role in biomedical and biochemical research. Common techniques that give full structural information do not permit in-vivo measurements. Infrared spectroscopy has a sufficient sensitivity to examine the structure of proteins solution under in-situ conditions and even on surfaces. However, measurements at few spots on the surface are not suitable to find out the blood compatibility of the protein layer, because the changes in conformation occur often in small domains. Here we report on the investigations of adsorbed fibrinogen with FTIR imaging. FTIR imaging permits an identification of coagulation spots in the micrometer range and the identification of coagulation spots on the implant material.

Citation Download Citation

Gerald Steiner, Manfred Maitz, Sibel Tunc, and Reiner Salzer "Blood compatibility of artificial blood vessels probed by infrared spectroscopic imaging", Proc. SPIE 6093, Biomedical Vibrational Spectroscopy III: Advances in Research and Industry, 609302 (10 February 2006); https://doi.org/10.1117/12.644997

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available