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27 March 2006 Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors
Sandra Miskoski, Luciana Giordano, Maria H. Etchehon, Guillermo Menendez, Keith A. Lidke, Guy M. Hagen, Thomas M. Jovin, Elizabeth A. Jares-Erijman
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Abstract
Multifunctional nanoparticles, quantum dots (QDs) are being developed as uniquely sensitive tools for elucidating the (bio)chemical and (bio)physical molecular mechanisms underlying functional states, i.e. the molecular physiology, of biological cells and organisms. Here we present a group of strategies and examples for (i) controlling the spectroscopic properties of QDs via Fluorescence Resonance Energy Transfer (FRET); (ii) determining the emission spectra of individual QDs in a population with an imaging spectrograph (ASI SpectraCube); and (iii) employing such liganded QDs as nano-probes in cellular studies of signal transduction.
© (2006) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Sandra Miskoski, Luciana Giordano, Maria H. Etchehon, Guillermo Menendez, Keith A. Lidke, Guy M. Hagen, Thomas M. Jovin, and Elizabeth A. Jares-Erijman "Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors", Proc. SPIE 6096, Colloidal Quantum Dots for Biomedical Applications, 60960X (27 March 2006); https://doi.org/10.1117/12.649835
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Cited by 4 scholarly publications.
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KEYWORDS
Fluorescence resonance energy transfer

Quantum dots

Modulation

Luminescence

Nanoparticles

Spectroscopy

Ultraviolet radiation

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