27 March 2006 Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors
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Abstract
Multifunctional nanoparticles, quantum dots (QDs) are being developed as uniquely sensitive tools for elucidating the (bio)chemical and (bio)physical molecular mechanisms underlying functional states, i.e. the molecular physiology, of biological cells and organisms. Here we present a group of strategies and examples for (i) controlling the spectroscopic properties of QDs via Fluorescence Resonance Energy Transfer (FRET); (ii) determining the emission spectra of individual QDs in a population with an imaging spectrograph (ASI SpectraCube); and (iii) employing such liganded QDs as nano-probes in cellular studies of signal transduction.
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Sandra Miskoski, Sandra Miskoski, Luciana Giordano, Luciana Giordano, Maria H. Etchehon, Maria H. Etchehon, Guillermo Menendez, Guillermo Menendez, Keith A. Lidke, Keith A. Lidke, Guy M. Hagen, Guy M. Hagen, Thomas M. Jovin, Thomas M. Jovin, Elizabeth A. Jares-Erijman, Elizabeth A. Jares-Erijman, } "Spectroscopic modulation of multifunctionalized quantum dots for use as biological probes and effectors", Proc. SPIE 6096, Colloidal Quantum Dots for Biomedical Applications, 60960X (27 March 2006); doi: 10.1117/12.649835; https://doi.org/10.1117/12.649835
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