A study of binding biotinylated nano-beads to the surface of (001) GaAs

Ximing Ding; Khalid Moumanis; Jan J. Dubowski; Eric H. Frost

doi:10.1117/12.660730

1 March 2006 A study of binding biotinylated nano-beads to the surface of (001) GaAs

Ximing Ding, Khalid Moumanis, Jan J. Dubowski, Eric H. Frost

Author Affiliations +

Proceedings Volume 6106, Photon Processing in Microelectronics and Photonics V; 61061L (2006) https://doi.org/10.1117/12.660730
Event: Lasers and Applications in Science and Engineering, 2006, San Jose, California, United States

Abstract

We have investigated the deposition of biotinylated nano-beads on the surface of GaAs. The deposition procedure involved either direct coating of (001) GaAs with nano-beads, or binding the nano-beads with avidin immobilized on the surface of (001) GaAs through the interface of biotin and the NH₂ terminal group of 11-amino-1-undecanethiol (HS(CH₂)₁₁NH₂). The efficiency of binding was tested by washing the samples in a solution of a commercial detergent and by subjecting them to a deionized water ultrasonic bath. The results indicate that nano-beads deposited directly on the surface of (001) GaAs withstand the detergent washing test but they are easily removed by ultrasonic washing. In contrast, the nano-beads attached to (001) GaAs through the avidin-biotin-thiol interface survive the ultrasonic washing tests.

Citation Download Citation

Ximing Ding, Khalid Moumanis, Jan J. Dubowski, and Eric H. Frost "A study of binding biotinylated nano-beads to the surface of (001) GaAs", Proc. SPIE 6106, Photon Processing in Microelectronics and Photonics V, 61061L (1 March 2006); https://doi.org/10.1117/12.660730

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