Measurements and simulations of the signal-difference-to-noise ratio (SDNR) and average glandular dose (AGD) have been performed on a photon counting full-field digital mammography system to determine the optimal operating conditions. Several beam qualities were experimentally evaluated by using different combinations of tube voltage, added filters and thickness of BR12 with a tungsten target
x-ray tube. The SDNR and AGD were also calculated theoretically for an extended number of operating conditions and a more accurate breast
model. As figure of merit for each operating condition, a spectral quantum efficiency (SQE) was calculated as the polychromatic SDNR squared over the optimal monochromatic SDNR squared at the same AGD. The theoretical model agreed within ±4% relative the measured SDNR throughout the evaluated breast thickness (30-70 mm) and tube voltage range (26-38 kV). The optimization was performed with a constant
SDNR-rate as compared to using a fixed filter thickness. The optimal combinations of tube voltage-filter material were: 32 kV-Ag, 34
kV-Cd, 36 kV-Sn for a breast thickness of 30, 50 and 70 mm respectively. These K-edge filter materials increased the SQE by less than 4% compared to the optimal Al filtration.
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