2 March 2006 Evaluation of a photon-counting breast tomosynthesis imaging system
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Abstract
Digital breast tomosynthesis promises solutions to many of the problems associated with projection mammography, including elimination of artifactual densities due to the superposition of normal tissues and increasing the conspicuity of true lesions that would otherwise be masked by superimposed normal tissue. We have investigated tomosynthesis using a digital camera containing 48 photon counting, orientation sensitive, linear detectors which are precisely aligned with the focal spot of the x-ray source. The x-ray source and the digital detectors are scanned in a continuous motion across the object (patient), each linear detector collecting an image at a distinct angle. A preliminary assessment of tomosynthesis image quality has been performed with both qualitative and quantitative methods. Measured values of MTF and NPS appear concordant with theoretical values. The MTF in the scanning direction is dominated by scanning unsharpness and geometric factors, while the NPS is white. The MTF and NPS in the strip direction are somewhat lower than in the scan direction. The NPS of tomographic images show a slight decrease with increasing spatial frequency, related to the sampling and interpolation in the reconstruction process. A phase I clinical trial is ongoing; 9 women have been recruited. Breast positioning is comparable to other imaging systems. The visualization of breast anatomy appears to be superior to screen-film mammography, at the same average glandular dose. Examination of images reconstructed with a sub-sampled set of projection images appears to support the hypothesis that image quality is superior when more projection images are used in the reconstruction.
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Andrew D. A. Maidment, Andrew D. A. Maidment, Christer Ullberg, Christer Ullberg, Karin Lindman, Karin Lindman, Leif Adelöw, Leif Adelöw, Johan Egerström, Johan Egerström, Mathias Eklund, Mathias Eklund, Tom Francke, Tom Francke, Ulf Jordung, Ulf Jordung, Tomas Kristoffersson, Tomas Kristoffersson, Lars Lindqvist, Lars Lindqvist, Daniel Marchal, Daniel Marchal, Hans Olla, Hans Olla, Erik Penton, Erik Penton, Juha Rantanen, Juha Rantanen, Skiff Solokov, Skiff Solokov, Niclas Weber, Niclas Weber, Hans Westerberg, Hans Westerberg, "Evaluation of a photon-counting breast tomosynthesis imaging system", Proc. SPIE 6142, Medical Imaging 2006: Physics of Medical Imaging, 61420B (2 March 2006); doi: 10.1117/12.654651; https://doi.org/10.1117/12.654651
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