2 March 2006 Application of x-ray computed tomography based on the refraction contrast to biomedicine
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We have developed X-ray refraction based computed tomography (CT) which is able to visualize soft tissue in between hard tissue. The experimental system consists of Si(220) diffraction double-crystals called the DEI (diffraction-enhanced imaging) method, object locating in between them and a CCD camera to acquire data of 900 x-ray images. The x-ray energy used was 17.5 keV. The algorithm used to reconstruct CT images has been invented by A. Maksimenko et al.. We successfully visualized calcification and distribution of breast cancer nest which are the inner structure. It has much higher contrast which in comparison with the conventional absorption based CT system.
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Eiko Hashimoto, Anton Maksimenko, Hiroshi Sugiyama, Kazuyuki Hyodo, Daisuke Shimao, Tetsuya Yuasa, Yoshinori Nishino, Tetsuya Ishikawa, Koichi Mori, Yoshinori Arai, Keiichi Hirano, Masami Ando, "Application of x-ray computed tomography based on the refraction contrast to biomedicine", Proc. SPIE 6142, Medical Imaging 2006: Physics of Medical Imaging, 614213 (2 March 2006); doi: 10.1117/12.654313; https://doi.org/10.1117/12.654313

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