2 March 2006 Single-photon spatial and energy resolution enhancement of a columnar CsI(Tl)/EMCCD gamma-camera using maximum-likelihood estimation
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Abstract
We examined the spatial resolution of a columnar CsI(Tl), single-photon imaging system using an approach that estimates the interaction position to better than the spread of the light distribution. A columnar scintillator was directly coupled to a 512×512 electron multiplying CCD (EMCCD) camera (16 μm pixels) binned at 2×2 to sample at 32 μm pixels. Optical photons from gamma-ray/scintillator interactions are sampled over multiple pixels. Resultant images show clusters of signal at the original interaction site, clusters from Cs and I K x-rays up to several hundred microns away, and clusters from collimator K x-rays. Also evident are depth-of-interaction effects which result in a broadening of the light distribution. These effects result in a degradation of spatial and energy resolution. Cluster pixel data was processed to better estimate the interaction position within the initial interaction cluster. Anger (centroid) estimation of individual gamma-ray events yielded spatial resolutions better than 100 μm; a result previously achievable only with pixellated semiconductor detector arrays. After proper calibration, depth-of-interaction (DOI) effects are corrected by performing maximum-likelihood 3D position and energy estimation of individual gamma-ray interactions.
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Brian W. Miller, H. Bradford Barber, Harrison H. Barrett, Irina Shestakova, Bipin Singh, Vivek V. Nagarkar, "Single-photon spatial and energy resolution enhancement of a columnar CsI(Tl)/EMCCD gamma-camera using maximum-likelihood estimation", Proc. SPIE 6142, Medical Imaging 2006: Physics of Medical Imaging, 61421T (2 March 2006); doi: 10.1117/12.652650; https://doi.org/10.1117/12.652650
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