13 March 2006 High resolution multidetector CT aided tissue analysis and quantification of lung fibrosis
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Abstract
Idiopathic pulmonary fibrosis (IPF, also known as Idiopathic Usual Interstitial Pneumontis, pathologically) is a progressive diffuse lung disease which has a median survival rate of less than four years with a prevalence of 15-20/100,000 in the United States. Global function changes are measured by pulmonary function tests and the diagnosis and extent of pulmonary structural changes are typically assessed by acquiring two-dimensional high resolution CT (HRCT) images. The acquisition and analysis of volumetric high resolution Multi-Detector CT (MDCT) images with nearly isotropic pixels offers the potential to measure both lung function and structure. This paper presents a new approach to three dimensional lung image analysis and classification of normal and abnormal structures in lungs with IPF.
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Vanessa A. Zavaletta, Vanessa A. Zavaletta, Ronald A. Karwoski, Ronald A. Karwoski, Brian Bartholmai, Brian Bartholmai, Richard A. Robb, Richard A. Robb, } "High resolution multidetector CT aided tissue analysis and quantification of lung fibrosis", Proc. SPIE 6143, Medical Imaging 2006: Physiology, Function, and Structure from Medical Images, 61432Z (13 March 2006); doi: 10.1117/12.653450; https://doi.org/10.1117/12.653450
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