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10 March 2006 Segmentation by surface-to-image registration
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This paper presents a new image segmentation algorithm using surface-to-image registration. The algorithm employs multi-level transformations and multi-resolution image representations to progressively register atlas surfaces (modeling anatomical structures) to subject images based on weighted external forces in which weights and forces are determined by gradients and local intensity profiles obtained from images. The algorithm is designed to prevent atlas surfaces converging to unintended strong edges or leaking out of structures of interest through weak edges where the image contrast is low. Segmentation of bone structures on MR images of rat knees analyzed in this manner performs comparably to technical experts using a semi-automatic tool.
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Zhiyong Xie, Jose Tamez-Pena, Michael Gieseg, Serguei Liachenko, Shantanu Dhamija, and Ping Chiao "Segmentation by surface-to-image registration", Proc. SPIE 6144, Medical Imaging 2006: Image Processing, 614405 (10 March 2006);

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