15 March 2006 Simulating nodules in chest radiographs with real nodules from multi-slice CT images
Author Affiliations +
Proceedings Volume 6144, Medical Imaging 2006: Image Processing; 614456 (2006); doi: 10.1117/12.651623
Event: Medical Imaging, 2006, San Diego, California, United States
To improve the detection of nodules in chest radiographs, large databases of chest radiographs with annotated, proven nodules are needed for training of both radiologists and computer-aided detection systems. The construction of such databases is a laborious and time-consuming task. This study presents a novel technique to produce large amounts of chest x-rays with annotated, simulated nodules. Realistic nodules in radiographs are generated using real nodules segmented from CT images. Results from an observer study indicate that the simulated nodules can not be distinguished from real nodules. This method has great potential to aid the development of automated detection systems and to generate teaching files for human observers.
© (2006) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Arnold Schilham, Bram van Ginneken, "Simulating nodules in chest radiographs with real nodules from multi-slice CT images", Proc. SPIE 6144, Medical Imaging 2006: Image Processing, 614456 (15 March 2006); doi: 10.1117/12.651623; https://doi.org/10.1117/12.651623


X-ray computed tomography

Chest imaging


Lung cancer

Image segmentation


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