Rapid NIR optical tomography at 35 frames per second by spectrally-encoded parallel light delivery

Daqing Piao; Hamid Dehghani; Shudong Jiang; Subhadra Srinivasan; Brian W. Pogue

doi:10.1117/12.696968

21 July 2006 Rapid NIR optical tomography at 35 frames per second by spectrally-encoded parallel light delivery

Daqing Piao, Hamid Dehghani, Shudong Jiang, Subhadra Srinivasan, Brian W. Pogue

Proceedings Volume 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII; 61630K (2006) https://doi.org/10.1117/12.696968
Event: Saratov Fall Meeting 2005, 2005, Saratov, Russian Federation

Abstract

NIR tomography has advanced considerably over the past decade. The historical developments which have led to creation of NIR tomography have largely resulted in systems which were optimized for signal accuracy and high numbers of point measurements, rather than speed of acquisition. One of the key technological designs limiting the acquisition speed is the requirement that the source light be delivered sequentially or through frequency encoding of the time signal. The approach presented here provides a method to introduce all sources and all detectors simultaneously with no moving parts and retaining the dynamic range of the detector, by separating the signals spatially prior to detection. This is achieved by spectral wavelength encoding of the sources, which allows many sources to be input into the tissue at the same time, followed by spectral-decoding of all detection channels in parallel using a spectrometer and CCD detector. A data acquisition speed of 35Hz frame rate has been achieved with this configuration. The described system features 8 sources at an overall 785nm center band and 8 detectors evenly deployed in a 27mm array designed for imaging with small animal tissues. This paper discusses the design, instrumentation of the system, and the imaging characteristics.

Citation Download Citation

Daqing Piao, Hamid Dehghani, Shudong Jiang, Subhadra Srinivasan, and Brian W. Pogue "Rapid NIR optical tomography at 35 frames per second by spectrally-encoded parallel light delivery", Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61630K (21 July 2006); https://doi.org/10.1117/12.696968

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
9 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Sensors

Imaging systems

Signal detection

Tomography

Spectroscopy

Charge-coupled devices

Absorption

Show All Keywords

Keywords/Phrases

Search In:

Publication Years