31 March 2006 Biomolecules as nanomaterials: interface characterization for sensor development
Author Affiliations +
Abstract
Extensive research is underway to understand and exploit the interface between biological materials and integrated systems Today, "nanotechnology" can be defined as a group of emerging technologies in which the structure of matter is controlled at the nanometer scale, the scale of small numbers of atoms, to produce novel materials and devices having useful and unique properties. An ideal biological candidate for use in nanoscale devices is the microtubule, an essential component of the eukaryotic cytoskeleton, which, unlike most proteins, has been shown to be electrically conductive. Due to the presence of an intrinsic dipole in the protein polymer, RF reflectance spectroscopy was chosen as an interrogation method. RF reflectance spectroscopy measures the electrical response of a sample in response to sinusoidally alternating currents as a function of frequency By interrogating the protein electrically, we are able to detect the polymerization state of the system, track any associated conductivity changes, and monitor binding of microtubule-associated proteins. We demonstrate manipulation of the microtubule system through the use of low-frequency electric fields, and discuss implications for sensor development.
© (2006) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Gregory Goddard, Jennifer E. Whittier, "Biomolecules as nanomaterials: interface characterization for sensor development", Proc. SPIE 6172, Smart Structures and Materials 2006: Smart Electronics, MEMS, BioMEMS, and Nanotechnology, 617206 (31 March 2006); doi: 10.1117/12.658771; https://doi.org/10.1117/12.658771
PROCEEDINGS
12 PAGES


SHARE
RELATED CONTENT

Ultra-efficient all-printed organic photodetectors
Proceedings of SPIE (September 27 2016)
Smart sensor chip based on bioMEMS
Proceedings of SPIE (March 29 2004)
Metal Rubber sensors
Proceedings of SPIE (May 16 2005)

Back to Top