Optical micromanipulation of synthetic macromolecules

Wolfgang Singer; Timo A. Nieminen; Norman R. Heckenberg; Halina Rubinsztein-Dunlop

doi:10.1117/12.680187

11 September 2006 Optical micromanipulation of synthetic macromolecules

Wolfgang Singer, Timo A. Nieminen, Norman R. Heckenberg, Halina Rubinsztein-Dunlop

Proceedings Volume 6326, Optical Trapping and Optical Micromanipulation III; 632619 (2006) https://doi.org/10.1117/12.680187
Event: SPIE Optics + Photonics, 2006, San Diego, California, United States

Abstract

Particles that can be trapped in optical tweezers range in size from tens of nanometres to tens of micrometres. Notably, this size range includes large single molecules. We show experimentally, in agreement with theoretical expectations, that optical tweezers can be used to manipulate single molecules of polyethylene oxide suspended in water. The trapped molecules accumulate without aggregating, so the optical trap offers a method of controlling the concentration of macromolecules in solution. Potential applications are the micromanipulation of nanoparticles, nanoassembly, microchemistry, and the study of biological macromolecules.

Citation Download Citation

Wolfgang Singer, Timo A. Nieminen, Norman R. Heckenberg, and Halina Rubinsztein-Dunlop "Optical micromanipulation of synthetic macromolecules", Proc. SPIE 6326, Optical Trapping and Optical Micromanipulation III, 632619 (11 September 2006); https://doi.org/10.1117/12.680187

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