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13 October 2006 Influenza viruses optical detection based on liquid crystals
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Human influenza viruses are common-acquired respiratory pathogens, influenza rapidly spreads around the world in seasonal epidemics. Methods of influenza viruses detection are based on application of spectroscopic and fluorescence technique. All of them couldn't visualize directly the influenza virus structure modifications, need few days for examination and consist many steps of operation. To avoid the disadvantages the new contact technique with high spatial resolution based on nematic liquid crystals (NLC) application was suggested. The free thin NLC layers applied on the surface under investigation and observed in polarizing microscope are being used in the science and high technologies for structural inhomogeneities detection on the surface of different materials. Simplicity, efficiency and high sensitivity have given an opportunity of universal NLC technique application in crystallography, mineralogy, metallography, thin film technology, medicine and biology. The new field of LC vision application in virus detecting and experimental results are discussed.
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M. G. Tomilin, S. K. Stafeev, and A. Stepanova "Influenza viruses optical detection based on liquid crystals", Proc. SPIE 6398, Optically Based Biological and Chemical Detection for Defence III, 639813 (13 October 2006);

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