Single-cell impedance spectroscopy: maximum length sequence analysis

Tao Sun; Nicolas G. Green; Shady Gawad; Hywel Morgan

doi:10.1117/12.696633

14 December 2006 Single-cell impedance spectroscopy: maximum length sequence analysis

Tao Sun, Nicolas G. Green, Shady Gawad, Hywel Morgan

Author Affiliations +

Proceedings Volume 6416, Biomedical Applications of Micro- and Nanoengineering III; 64160Y (2006) https://doi.org/10.1117/12.696633
Event: SPIE Smart Materials, Nano- and Micro-Smart Systems, 2006, Adelaide, Australia

Abstract

A novel broadband high-speed impedance spectrometer has been developed for the analysis of single biological particles in a high-throughput microfluidic cytometer. The technique is based on obtaining the impulse response of the system using maximum length sequences (MLS) as the excitation signal. The impulse response is converted into the frequency domain using Fast Fourier Transform (FFT). Theoretical modeling and simulation of a single cell suspended in the cytometer show that the MLS technique is capable of high precision single particle analysis.

Citation Download Citation

Tao Sun, Tao Sun, Nicolas G. Green, Nicolas G. Green, Shady Gawad, Shady Gawad, Hywel Morgan, Hywel Morgan, "Single-cell impedance spectroscopy: maximum length sequence analysis", Proc. SPIE 6416, Biomedical Applications of Micro- and Nanoengineering III, 64160Y (14 December 2006); doi: 10.1117/12.696633; https://doi.org/10.1117/12.696633

ACCESS THE FULL ARTICLE

PERSONAL SIGN IN
Full access may be available with your subscription

Email or Username Forgot your username?

Password Forgot your password?

Show

Remember Email/Username on this computer

Remember Password

No SPIE account? Create an account
or Institutional Sign In via Shibboleth

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $14.40

Non-members: $18.00 ADD TO CART

Show All Keywords

Keywords/Phrases

Search In:

Publication Years