23 March 2007 Ex-vivo investigations on endoluminal vein treatment procedures
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Abstract
An ex-vivo model was developed for experimental evaluation of endoluminal thermal procedures for the occlusion of saphenous veins. The model consists of the subcutaneous foot vein from freshly slaughtered cows. Using this model primary and acute effects and initial mechanisms on vein vessel could be studied. In this study different energy sources (laser and radiofrequency generator), different energy application parameters (velocity, fluence, fluence rate, temperature) were compared. The dependency of using bare fibre and cylindrical diffusors could be investigated with respect to the induced effects on the vessels wall. Contraction of the vessels were measured and investigated macroscopically and microscopically as well as by means of optical coherence tomography. As a result an optimized treatment protocol could be developed and discussed with respect to the induced effects.
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R. Sroka, R. Sroka, C. Burgmeier, C. Burgmeier, Oliver Meissner, Oliver Meissner, Katrin Hunger, Katrin Hunger, Gregor Barbaryka, Gregor Barbaryka, W. Beyer, W. Beyer, T. Beck, T. Beck, B. Steckmeier, B. Steckmeier, C. Schmedt, C. Schmedt, } "Ex-vivo investigations on endoluminal vein treatment procedures", Proc. SPIE 6424, Photonic Therapeutics and Diagnostics III, 64240M (23 March 2007); doi: 10.1117/12.700213; https://doi.org/10.1117/12.700213
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