27 March 2007 Convergence analysis and preliminary experimental feasibility for MRI-localized region spectroscopy with NIR diffuse optical tomography
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Abstract
NIR tomography image reconstruction can be improved by incorporating spectral constraints and prior spatial information. The convergence of scattering power was studied based on the distribution of projection error with different parameters. The reason that scattering properties are harder to recover than chromophore concentrations was discussed. Using "hard prior" spectral reconstruction, the role of stopping criteria was found to be important. Multiple wavelength simulations were used to choose suitable stopping criteria. Preliminary tests using a wavelength tunable Ti-Sapphire laser shows promise for frequency domain measurements covering a wide range of wavelengths.
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Jia Wang, Jia Wang, Scott Davis, Scott Davis, Shudong Jiang, Shudong Jiang, Brian W. Pogue, Brian W. Pogue, Keith D. Paulsen, Keith D. Paulsen, } "Convergence analysis and preliminary experimental feasibility for MRI-localized region spectroscopy with NIR diffuse optical tomography", Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 64341B (27 March 2007); doi: 10.1117/12.699371; https://doi.org/10.1117/12.699371
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