13 February 2007 Design and evaluation of a simultaneous fNIRS/ERP instrument
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Abstract
Functional Near-Infrared Spectroscopy (fNIRS) is a powerful non-invasive method to measure hemodynamic changes in tissues, while electroencephalography (EEG) provides excellent neuronal-electrical information in functional brain mapping. We developed an fNIRS/ERP instrument which can concurrently monitor the electrical neuronal activation and the hemodynamic response for the study of neurovascular coupling of the human brain. The probe of the instrument consists of 1 LED operating at three different wavelengths (735 nm & 805 nm & 850 nm) and 2 photodiodes (PDs) with the interoptode distance up to 3 cm, and an Ag-AgCl electrode lies in the center of the LED-PD pairs. The four components are encapsulated in a black sponge to decrease the interference of outside light as well as facilitate the placement on the forehead. The signals from the PDs and the electrode separately pass though two adjustable amplify-filter circuits which amplify the weak signals and block the high frequency interferences. A high speed data acquisition board samples the modulated signals under the control of a home-made software. The time resolution of the instrument achieves less than 10ms, which makes it realizable to compare the fNIRS data with the ERP data.
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Li Li, Li Li, Peng Du, Peng Du, Ting Li, Ting Li, Qingming Luo, Qingming Luo, Hui Gong, Hui Gong, } "Design and evaluation of a simultaneous fNIRS/ERP instrument", Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 643429 (13 February 2007); doi: 10.1117/12.701730; https://doi.org/10.1117/12.701730
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