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6 February 2007 An observation of ablation effect of soft biotissue by pulsed Er:YAG laser
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Because of the unique properties with regard to the absorption in organic tissue, pulsed Er:YAG laser has found most interest for various application in medicine, such as dermatology, dentistry, and cosmetic surgery. However, consensus regarding the optimal parameters for clinical use of this tool has not been reached. In this paper, the laser ablation characteristics of soft tissue by Er:YAG laser irradiation was studied. Porcine skin tissue in vitro was used in the experiment. Laser fluences ranged from 25mJ/mm2 to 200mJ/mm2, repetition rates was 5Hz, spot sizes on the tissue surface was 2mm. The ablation effects were assessed by the means of optical microscope, ablation diameters and depths were measured with reading microscope. It was shown that the ablation of soft biotissue by pulsed Er:YAG laser was a threshold process. With appropriate choice of irradiation parameters, high quality ablation with clean, sharp cuts following closely the spatial contour of the incident beam can be achieved. The curves of ablation crater diameter and depth versus laser fluence were obtained, then the ablation threshold and ablation yield were calculated subsequently, and the influence of the number of pulses fired into a crater on ablation crater depth was also discussed.
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Xianzeng Zhang, Shusen Xie, Qing Ye, and Zhenlin Zhan "An observation of ablation effect of soft biotissue by pulsed Er:YAG laser", Proc. SPIE 6435, Optical Interactions with Tissue and Cells XVIII, 64350D (6 February 2007);

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