7 February 2007 Effect of erythrocyte aggregation on optical transmission of blood
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We present here a bird-eye view of time-dependent optical transmission of blood in red-near infrared spectral range. This issue is of the key importance both for fundamental understanding and for various applications connected with non-invasive optical blood analysis. A number of experiments measuring kinetics of blood transmission in the case of natural heart pulsations and of artificial kinetics following over-systolic occlusion is reviewed. The comprehensive theoretical approach has to consider scattering-associated mechanism rather than the widely accepted absorption-associated one. Light scattering occurs on RBC aggregates. The size of aggregates and their shape change in time due to blood flow variations. It results in the corresponding changes of optical transmission.
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L. D. Shvartsman, L. D. Shvartsman, I. Fine, I. Fine, } "Effect of erythrocyte aggregation on optical transmission of blood", Proc. SPIE 6436, Complex Dynamics and Fluctuations in Biomedical Photonics IV, 64360B (7 February 2007); doi: 10.1117/12.700662; https://doi.org/10.1117/12.700662

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