14 February 2007 Depth sensitivity of laser Doppler perfusion imager: quantification based on experiments and Monte Carlo simulations on static and dynamic scattering phantoms
Author Affiliations +
Proceedings Volume 6445, Optical Diagnostics and Sensing VII; 644506 (2007); doi: 10.1117/12.698519
Event: SPIE BiOS, 2007, San Jose, California, United States
Abstract
We report on a theoretical/experimental model to predict the depth sensitivity of laser Doppler perfusion imager. Further more we show the quantitative influence of speckles on laser Doppler perfusion imager response to scattering at different depths. The model is based on Monte Carlo simulations and experiments on static and dynamic scattering phantoms made of polystyrene microspehers. The experimental results are in good agreement with our theoretical predictions. The results show that the depth sensitivity of the laser Doppler perfusion imager is influenced by the speckles. The effects are big, especially when a narrow beam is used for measurement. We propose that a correction method should be developed based on speckle size in order to have a reliable blood perfusion information independent of tissue optical properties.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Vinayakrishnan Rajan, Babu Varghese, Ton G van Leeuwen, Wiendelt Steenbergen, "Depth sensitivity of laser Doppler perfusion imager: quantification based on experiments and Monte Carlo simulations on static and dynamic scattering phantoms", Proc. SPIE 6445, Optical Diagnostics and Sensing VII, 644506 (14 February 2007); doi: 10.1117/12.698519; https://doi.org/10.1117/12.698519
PROCEEDINGS
8 PAGES


SHARE
KEYWORDS
Photons

Doppler effect

Laser scattering

Scattering

Speckle

Imaging systems

Monte Carlo methods

RELATED CONTENT


Back to Top