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16 February 2007 Specifying tissue optical properties using axial dependence of confocal reflectance images: confocal scanning laser microscopy and optical coherence tomography
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Abstract
The optical properties of a tissue can be specified by the depth dependence of a reflectance-mode confocal measurement, as the focus is scanned down into a tissue. Reflectance-mode confocal scanning laser microscopy (rCSLM) and optical coherence tomography in focus tracking mode (OCT) are two examples of such confocal measurements. The measurement of reflected signal as a function of the depth of focus, R(z), is expressed as ρe-μz, where ρ [dimensionless] is the local reflectivity from the focus within a tissue and μ [cm-1] is the attenuation of signal as a function of z. The reflectivity of a mirror defines ρ = 1. This paper describes how the experimental ρ and μ map into the optical properties of scattering coefficient, μs [cm-1], and anisotropy of scattering, g [dimensionless]. Preliminary results on tissue for the rCSLM and OCT systems are reported.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
S. Jacques, R. Samatham, N. Choudhury, and D. S. Gareau "Specifying tissue optical properties using axial dependence of confocal reflectance images: confocal scanning laser microscopy and optical coherence tomography", Proc. SPIE 6446, Biomedical Applications of Light Scattering, 64460N (16 February 2007); https://doi.org/10.1117/12.716535
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