A pulse laser of ultraviolet region was used to form the flow path and so on. Numbers of heat-hardening resin-films and
fluoro resins were piled up a soda glass. A laser fabricated a part of the channel at the each film every lamination, and
then 3-D structure micro-channel was fabricated. The channel sizes are widths of 10-400&mgr;m and depths of 30-90&mgr;m.
Moreover through holes as artificial capillary-vessels are made in the resin having a minimum diameter of 5 &mgr;m and a
length of 100 &mgr;m. As bloods were injected into a particle focusing micro-channel, an artificial capillary-vessel, and a
micro-separator, then cell sort, erythrocyte deformability, and blood plasma were observed with a microscope,