22 March 2007 Clinical determination of target registration error of an image-guided otologic surgical system using patients with bone-anchored hearing aids
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Abstract
Image guidance in otologic surgery has been thwarted by the need for a non-invasive fiducial system with target registration error (TRE) at the inner ear below 1.5mm. We previously presented a fiducial frame for this purpose that attaches to the upper dentition via patient-specific bite blocks and demonstrated a TRE of 0.73mm (±0.23mm) on cadaveric skulls. In that study, TRE measurement depended upon placement of bone-implanted, intracranial target fiducials-clearly impossible to repeat clinically. Using cadaveric specimens, we recently presented a validation method based on an auditory implant system (BAHA System®; Cochlear Corp., Denver, CO). That system requires a skull-implanted titanium screw behind the ear upon which a bone-anchored hearing aid (BAHA) is mounted. In our validation, we replace the BAHA with a fiducial marker to permit measurement of TRE. That TRE is then used to estimate TRE at an internal point. While the method can be used to determine accuracy at any point within the head, we focus in this study on the inner ear, in particular the cochlea, and we apply the method to patients (N=5). Physical localizations were performed after varying elapsed times since bite-block fabrication, and TRE at the cochlea was estimated. We found TRE to be 0.97mm at the cochlea within one month and 2.5mm after seven months. Thus, while accuracy deteriorates considerably with delays of seven months or more, if this frame is used within one month of the fabrication of the bite-block, it achieves the goal and in fact exhibits submillimetric accuracy.
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Ramya Balachandran, Ramya Balachandran, Robert F. Labadie, Robert F. Labadie, J. Michael Fitzpatrick, J. Michael Fitzpatrick, } "Clinical determination of target registration error of an image-guided otologic surgical system using patients with bone-anchored hearing aids", Proc. SPIE 6509, Medical Imaging 2007: Visualization and Image-Guided Procedures, 650930 (22 March 2007); doi: 10.1117/12.709949; https://doi.org/10.1117/12.709949
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