19 March 2007 A wavelet based method for SPECT reconstruction with non-uniform attenuation
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SPECT (single photon emission computed tomography) is a tomography technique that can greatly show information about the metabolic activity in body and improve clinical diagnosis. In SPECT, because of photoelectric absorption and Compton scattering, the emitted gamma photons are attenuated inside the body before arriving at the detector. The goal of quantitative SPECT reconstruction is to obtain an accurate reconstructed image of the radioactivity distribution in the interested area of a human body, so the compensation for non-uniform attenuation is necessary in the quantitative SPECT reconstruction. In this paper, based on the explicit inversion formula for the attenuated Radon transform discovered by R. Novikov, we present a wavelet based SPECT reconstruction algorithm with non-uniform attenuation. We know that the wavelet transform has characteristics of multi-resolution analysis and localized analysis, and these characteristics can be applied to de-noising and localized reconstruction. Simulation results show that our wavelet based SPECT reconstruction algorithm is accurate.
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Junhai Wen, Junhai Wen, Lingkai Kong, Lingkai Kong, } "A wavelet based method for SPECT reconstruction with non-uniform attenuation", Proc. SPIE 6510, Medical Imaging 2007: Physics of Medical Imaging, 65104W (19 March 2007); doi: 10.1117/12.708923; https://doi.org/10.1117/12.708923

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