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31 March 2007 Automatic landmark detection for cervical image registration validation
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Many cervical Computer-Aided Diagnosis (CAD) methods rely on measuring gradual appearance changes on the cervix after the application of a contrast agent. Image registration has been used to ensure pixel correspondence to the same tissue location throughout the whole temporal sequence but, to date, there is no reliable mean of testing its accuracy to compensate for patient and tissue movement. We present an independent system to use automatically extracted and matched features from a colposcopic image sequence in order to generate position landmarks. These landmarks may be used either to measure the accuracy of a registration method to align any pair of images from the colposcopic sequence or as a cue for registration. The algorithm selects sets of matched features that extend through the whole image sequence allowing to locate, in a reliable and unbiased way, a tissue point throughout the whole image sequence. Experiments on real colposcopy image sequences show that the approach is robust, reliable, and leads to geometrically coherent sets of landmarks that correspond to visually recognizable regions. We use the extracted landmarks to test the precision of some of the cervical registration algorithms previously presented in the literature.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Juan D. García-Arteaga and Jan Kybic "Automatic landmark detection for cervical image registration validation", Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 65142S (31 March 2007);

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