Noninvasive measurement of glucose concentration using OCT based on the extended Huygens-Fresnel principle

Xuefang Li; Youwu He; Zhifang Li; Hui Li

doi:10.1117/12.741124

1 May 2007 Noninvasive measurement of glucose concentration using OCT based on the extended Huygens-Fresnel principle

Xuefang Li, Youwu He, Zhifang Li, Hui Li

Proceedings Volume 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine; 65340E (2007) https://doi.org/10.1117/12.741124
Event: Fifth International Conference on Photonics and Imaging in Biology and Medicine, 2006, Wuhan, China

Abstract

We have developed a noninvasive method to monitor the glucose concentration in tissue phantom used the OCT model which based on the extended Huygens-Fresnel (EHF) principle. The changes of the optical properties such as the scattering coefficient μ_s, the anisotropy factor g and the effective scattering coefficient μ_s with the increase of the glucose concentration in 10% Intralipid solution were obtained. The results showed that the scattering coefficient μ_s decreased when the glucose concentration increased in the solution, which is accorded with the conclusions by others. Contrarily, the factor g increased when the glucose concentration grown up. As a result, the coefficient μ_s is fall with the increased of the glucose concentration. Comparing with those previously reported in which only got the relative value of scattering coefficient μ_s, the most important advantage of our model is that we got the practical value of μ_s, g and μ_s. All of these reveal that the OCT EHF model is a promising method which is adapted to detect the glucose concentration in solution, and it will be applied in medical fields someday.

Citation Download Citation

Xuefang Li, Youwu He, Zhifang Li, and Hui Li "Noninvasive measurement of glucose concentration using OCT based on the extended Huygens-Fresnel principle", Proc. SPIE 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, 65340E (1 May 2007); https://doi.org/10.1117/12.741124

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