Determining tissue optical properties by optical coherence tomography

Kai Wang; Zhihua Ding; Ling Wang

doi:10.1117/12.741125

1 May 2007 Determining tissue optical properties by optical coherence tomography

Kai Wang, Zhihua Ding, Ling Wang

Proceedings Volume 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine; 65340F (2007) https://doi.org/10.1117/12.741125
Event: Fifth International Conference on Photonics and Imaging in Biology and Medicine, 2006, Wuhan, China

Abstract

Accurate measurement of tissue optical properties becomes more and more important in biomedical applications such as diagnostic imaging for tissue pathology. Taking account of multiple scattering effects in OCT model, an algorithm is developed to extract depth-resolved tissue optical properties including scattering coefficient and anisotropy factor. By adding absorption coefficient as the third fitting parameter in the algorithm, it is possible to reduce fitting errors introduced by sample absorption. With an adapted algorithm based on the extended model, absorption coefficient can also be extracted. The validity of those algorithms is verified by sample model of solution of polyethylene sphere (PS).

Citation Download Citation

Kai Wang, Zhihua Ding, and Ling Wang "Determining tissue optical properties by optical coherence tomography", Proc. SPIE 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, 65340F (1 May 2007); https://doi.org/10.1117/12.741125

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